Disease: Hypercholesterolemia
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
XDH P47989 xanthine dehydrogenase Enzyme 2.6E-22 0.529 0.846
VEGFA P15692 vascular endothelial growth factor A Signaling 2.4E-05 0.266 0.923
TNFRSF11B O00300 TNF receptor superfamily member 11b 0.16 0.422 0.808
TNF P01375 tumor necrosis factor Signaling 0.80 0.231 0.962
STAT3 P40763 signal transducer and activator of transcription 3 Nucleic acid binding 1.00 0.320 0.923
SLC5A2 P31639 solute carrier family 5 member 2 Transporter 4.9E-14 0.499 0.769
SIRT1 Q96EB6 sirtuin 1 Epigenetic regulator 8.7E-02 0.378 0.885
REN P00797 renin Enzyme 2.4E-07 0.370 0.923
RARRES2 Q99969 retinoic acid receptor responder 2 2.7E-05 0.519 0.731
PPARG P37231 peroxisome proliferator activated receptor gamma Nuclear receptor 2.9E-02 0.358 0.885
PPARA Q07869 peroxisome proliferator activated receptor alpha Nuclear receptor 3.0E-02 0.432 0.885
PON1 P27169 paraoxonase 1 9.8E-11 0.409 0.885
PLA2G7 Q13093 phospholipase A2 group VII Enzyme 5.3E-22 0.537 0.769
PHKG2 P15735 phosphorylase kinase catalytic subunit gamma 2 Kinase 3.9E-03 0.674 0.538
PHKA2 P46019 phosphorylase kinase regulatory subunit alpha 2 Kinase 0.38 0.678 0.462
NR3C2 P08235 nuclear receptor subfamily 3 group C member 2 Nuclear receptor 0.84 0.469 0.846
NLRP3 Q96P20 NLR family pyrin domain containing 3 8.1E-04 0.361 0.962
MTOR P42345 mechanistic target of rapamycin kinase Kinase 1.00 0.343 0.885
MTHFR P42898 methylenetetrahydrofolate reductase 3.2E-10 0.337 0.885
MAPK3 P27361 mitogen-activated protein kinase 3 Kinase 3.7E-02 0.379 0.885
LRP2 P98164 LDL receptor related protein 2 1.00 0.491 0.846
KLF2 Q9Y5W3 Kruppel like factor 2 Nucleic acid binding 0.56 0.542 0.692
IL6 P05231 interleukin 6 0.32 0.248 0.962
IL1B P01584 interleukin 1 beta 0.13 0.276 0.962
IL10 P22301 interleukin 10 5.9E-03 0.281 0.923